

MeSsy with Christina Applegate & Jamie Lynn Sigler
Wishbone Production
On this podcast, Christina Applegate and Jamie Lynn Sigler get vulnerable about the curveballs that life can throw…theirs just happens to be MS. Join them each week as they self-reflect, learn, laugh, and grow through their own raw and often-times hilarious conversations with each other, friends, co-stars, and the people that keep them going through the messiness of life.
Episodes
Mentioned books

Jan 20, 2026 • 47min
I’m a F**king Warrior
This week, Christina and Jamie read listener emails and discuss Jamie’s recent trip, pregnancy and MS, asking for help, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Wildgrain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants for life - when you go to Wildgrain.com/MESSY to start your subscription today.
Veracity - For up to 45% off your order, head to https://VeracityHealth.co and use code MESSY

Jan 13, 2026 • 1h 3min
The Impact of Inflammation with Dr. Will Cole
This week, Christina and Jamie are joined by Dr. Will Cole, a functional medicine expert. They discuss how to calm inflammation, medical gaslighting, the interactions between all our systems, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR with code MESSY at https://mudwtr.com/messy #mudwtrpod
Grow TherapyWhatever challenges you’re facing, Grow Therapy is here to help. Sessions average about $21 with insurance and some pay as little as $0, depending on their plan. Visit https://GrowTherapy.com/MESSY today to get started.

Jan 6, 2026 • 59min
This Is Not Your Fault
This week, Christina and Jamie read listener emails and discuss repeat reality stars, being a mother with MS, not blaming yourself, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Honeylove - Save 20% Off Honeylove by going to https://honeylove.com/messy #honeylovepod
Jones Road Beauty - Use code Messy at https://jonesroadbeauty.com to get a Free Cool Gloss with your first purchase! #JonesRoadBeauty #ad

Dec 30, 2025 • 1h
There’s a Lot of Unknown in Life
This week, Christina and Jamie read listener emails and discuss Christmas elves, setting goals, reclaiming your voice, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Calm - Calm has an exclusive offer just for listeners of our show – get 40% off a Calm Premium Subscription at https://calm.com/messy
Ridwell - Go to ridwell.com/messy to get $10 off your first pickup or mail-in kit. Because sometimes the best way to do more is just to start with something small that you know makes a difference.
Hexclad - Take advantage of HexClad’s Holiday Sale! Head to hexclad.com/MESSY for Up To 50% Off! #hexcladpartner

Dec 16, 2025 • 1h 16min
Are You Mad At Me? with Meg Josephson
This week, Christina and Jamie are joined by Meg Josephson, author of “Are You Mad at Me?: How to Stop Focusing on What Others Think and Start Living for You.” They discuss the fawn response, how to start healing, the importance of taking a pause, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
ZocDoc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today. Wild Grain - Wildgrain is offering our listeners $30 off your first box - PLUS free Croissants in every box - when you go to https://Wildgrain.com/MESSY to start your subscription.
iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at https://irestore.com/MESSY #irestorepod
Lola Blankets - Lola BlanketsGet 40% off your entire order at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.

Dec 9, 2025 • 1h 18min
Montel Williams
This week Christina and Jamie are joined by Montel Williams. They discuss his experience living with MS, bedside manner, why being ill doesn’t make you weak, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Fatty15 - Fatty15 is on a mission to optimize your C15 levels to help support your long-term health and wellness -Get an additional 15% off their 90-day subscription Starter Kit at fatty15.com/MESSY and using code MESSY at checkout.
Tushy - Over 2 Million Butts Love TUSHY. Get 10% off TUSHY with the code MESSY at https://hellotushy.com/MESSY
True Classic - Upgrade your wardrobe and save on @trueclassic at trueclassic.com/MESSY #trueclassicpod
Ridwell - Head to ridwell.com/messygift. It’s super easy — you can get a digital link to share instantly, or, if you know their address, have a kit mailed straight to your friends and family. Pro tip: if you’re not using Ridwell yet, treat yourself to one too… maybe that free third one!

Dec 2, 2025 • 56min
We're All Crushing It
This week, Christina and Jamie read listener emails and discuss perspective, not stuffing your feelings down, journaling, and much more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Nobl - Don’t miss NOBL’s biggest Sale of the Year! Head to NOBLTravel.com for up to 62% off your entire order! #NOBL #ad
Lola Blankets - Get 40% off your entire order at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.
Hollow Socks - For a limited time Hollow Socks is having a Buy 2, Get 2 Free Sale. Head to Hollowsocks.com today to check it out. #Hollow Sockspod
Honeylove - Save 20% Off Honeylove by going to honeylove.com/MESSY! #honeylovepod
Magic Spoon - Get 5 dollars off your next order at MagicSpoon.com/MESSY. Or look for Magic Spoon on Amazon or in your nearest grocery store.

Nov 25, 2025 • 1h 24min
How to Feel Safe in Your Body with Deb Dana (Re-Release)
This week, Christina and Jamie are revisiting their conversation with Deb Dana, LCSW, a clinician and speaker specializing in complex trauma. They discuss how to understand our nervous systems, polyvagal theory, how to feel safe in a body that may feel unsafe, and more.
Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This show is sponsored by:
Ridwell - Try Ridwell at ridwell.com/messy to get $10 off your first pickup or mail-in kit.
iRESTORE - Illumina Masks:Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/MESSY! #irestorepod
Calm -Calm has an exclusive offer just for listeners of our show–
get 40% off a Calm Premium Subscription at calm.com/messy.
Honeylove - Save 20% Off Honeylove by going to honeylove.com/MESSY! #honeylovepod
Tushy - Over 2 million butts love TUSHY. Get 10% off Tushy with the code MESSY at https://hellotushy.com/messy !

Nov 18, 2025 • 1h 7min
You Don’t Deserve to Feel Guilt
This week, Christina and Jamie read listener emails and discuss big feelings, reality dating shows, guilt, and more.
Executive Producers: Christina Applegate, Jamie Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Zoc Doc - Stop putting off those doctors appointments and go to Zocdoc.com/MESSY to find and instantly book a top-rated doctor today.
MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR at mudwtr.com/messy #mudwtrpod
Lola Blankets - Get 40% off your entire order at Lolablankets.com by using code MESSY at checkout. Experience the world’s #1 blanket with Lola Blankets.
True Classic - Upgrade your wardrobe and save on @trueclassic at trueclassic.com/messy #trueclassicpod
iRestore - Unlock your best skin with @iRestorelaser and HUGE savings on the iRestore Illumina Face Mask with code MESSY at irestore.com/messy #irestorepod

Nov 11, 2025 • 1h 12min
Best of MeSsy: Edie Falco, Jean Smart, and Katey Sagal
This week, we revisit conversations with three incredible guests: Edie Falco, Jean Smart, and Katey Sagal.
Executive Producers: Christina Applegate, Jamie-Lynn Sigler, and Allison Bresnick
Audio Engineer: Josh Windisch
This episode is sponsored by:
Ridwell - Try Ridwell at ridwell.com/messy to get $10 off your first pickup or mail-in kit.Hollow Socks - For a limited time Hollow Socks is having a Buy 3, Get 3 Free Sale. Head to Hollowsocks.com today to check out their huge sale. #Hollow Sockspod
MudWtr - Start your new morning ritual & get up to 43% off your @MUDWTR at mudwtr.com/messy! #mudwtrpod
Honeylove - Save 20% Off Honeylove by going to honeylove.com/messy. #honeylovepod
Cozy Earth - Black Friday has come early at Cozy Earth! Right now, you can stack my code MESSY on top of their sitewide sale — giving you up to 40% off in savings. That’s CozyEarth.com, code MESSY


