The Body of Evidence

Flu: Cold vs. flu; the anatomy of a virus; when viruses make a MegaZord; diagnosing, preventing and testing for the flu // coronavirus disease COVID-19 // update on talc and ovarian cancer   * Vox pop by David Lonstein * Jingle by Jillian Correia of Roctavio Canada * Additional music by Seth Donnelly and Kevin MacLeod of Incompetech.com. * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   Jonathan’s upcoming public events: https://jonathanjarry.com/category/events/ And Chris will be at ComSciConCan 2020: https://comscicon.com/comscicon-can-2020   Reference: 1) JAMA paper on talc and ovarian cancer: https://jamanetwork.com/journals/jama/article-abstract/2758452

Jonathan and Chris speak to Stephan Guyenet, Ph.D., the author of the book The Hungry Brain and the creator of the health book review site Red Pen Reviews, about hunger, obesity, and the highs and lows of debating a journalist on one of the biggest platforms on the Internet.   0:00 Introduction 2:00 How evolution shaped our brain 3:20 Hunger 9:00 The disconnect between hunger and energy needs 15:12 The stressed-out brain of an obese mouse 18:54 Weight loss drugs targeting the brain 21:50 It’s a thermostat… but not really 28:00 Stress and obesity 29:44 Debating journalist Gary Taubes on The Joe Rogan Experience 36:14 False balance on massive platforms 39:32 Rhetoric and the unstructured debate 44:42 Stephan’s eating habits 47:54 Informative reviews of health and nutrition books 51:40 Rewards: food, sex and gold   * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   Links: 1) Stephan’s book, The Hungry Brain: https://www.goodreads.com/book/show/29243729-the-hungry-brain 2) Stephan’s website: https://www.stephanguyenet.com/ 3) Stephan Guyenet on Twitter: https://twitter.com/whsource 4) Red Pen Reviews: https://www.redpenreviews.org/ 5) Stephan on the Joe Rogan Experience: https://youtu.be/vA3QavPp1Ho

Salt: what is it and what does it do to the body? (with Star Wars references!) // Telling Australians to stop drinking // Q&A with our listeners // YouTube cracks down on pseudomedicine   * Vox pop by David Lonstein * Jingle by Joseph Hackl * Additional music by Seth Donnelly and Kevin MacLeod of Incompetech.com. * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   References: 1) Review of MSG: https://www.ncbi.nlm.nih.gov/pubmed/10736382 2) Sources of sodium: He FJ, MacGregor GA. Reducing population salt intake worldwide: from evidence to implementation. Prog Cardiovasc Dis 2010; 52:363. 3) DASH diet study: https://www.ncbi.nlm.nih.gov/pubmed/11136953 4) TOHP study: https://www.bmj.com/content/334/7599/885.long 5) John Ioannidis’ editorial: https://academic.oup.com/ije/article/45/1/264/2364034 6) Prison study editorial: https://www.ahajournals.org/doi/10.1161/HYPERTENSIONAHA.118.11103 7) Alcohol Abstinence in Drinkers with Atrial Fibrillation: https://www.nejm.org/doi/full/10.1056/NEJMoa1817591

One day, Trysha Gellis’ heart just stopped pumping blood. She lost consciousness and almost died… but CPR saved her life. Today, we hear her story and our medical experts explain what doctors do to investigate what went wrong with her heart on that day. Thankfully, it involves cute anesthesiologists. * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra. To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/. Patrons get a bonus show on Patreon called “Digressions”! Check it out! References: 1) Living Proof CPR Training: https://www.livingproofcpr.com 2) Heart and Stroke Foundation of Canada’s CPR Videos: https://www.heartandstroke.ca/get-involved/learn-cpr

Drinking water: alkaline, thirst, bottled, lead // Interview with Olivier Bernard (thepharmafist.com) on vitamin C, harassment, and winning the John Maddox Prize // Vaping update: EVALI and popcorn lung   * Vox pop by Sarah Swinwood * Jingle by Jillian Correia of Roctavio Canada * Additional music by Seth Donnelly and Kevin MacLeod of Incompetech.com. * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   References: 1) The JAMA study on water intake and kidney function: https://jamanetwork.com/journals/jama/fullarticle/2680548 2) Filter numbers: http://info.nsf.org/Certified/DWTU/listings_leadreduction.asp; http://www.nsf.org/consumer-resources/water-quality/water-filters-testing-treatment/standards-water-treatment-systems 3) Places where you can test your water in Quebec: http://www.ceaeq.gouv.qc.ca/accreditation/PALA/lla03.htm?fbclid=IwAR2u1zqvmnb03uklvROVsjCPsLqljFdUcjO2qv3tM0XMyQJhRCRzLokkCMA#outaouais 4) SWET Trial: https://www.ncbi.nlm.nih.gov/pubmed/21324289  

Chris and Jonathan were interviewed on stage by a reporter from the McGill Tribune newspaper as part of their annual conference on journalism and the media. They discuss how they met, their respective backgrounds, the challenges of podcasting, and many more. Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra. To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.

Prostate cancer: how common, how to detect it, how to treat it (should we?) // Artificial lights and sleep with Morgan Sweeney // Should we really be eating more meat now?   * Vox pop by David Lonstein * Jingle by Joseph Hackl of Voodoo Jazz * Additional music by Seth Donnelly and Kevin MacLeod of Incompetech.com (including "House of Leaves"). * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   References: 1) ERSPC randomized trial of prostate cancer screening: https://www.ncbi.nlm.nih.gov/pubmed/?term=10.1016%2Fj.eururo.2012.05.068 2) ERSPC randomized trial of prostate cancer screening: https://www.ncbi.nlm.nih.gov/pubmed/30824296 3) Quality of Life study: https://www.nejm.org/doi/full/10.1056/NEJMoa1201637 4) Chemoprevention study 1, PCPT: https://www.nejm.org/doi/full/10.1056/NEJMoa1215932 5) Chemoprevention study 2, REDUCE: https://www.nejm.org/doi/full/10.1056/NEJMoa0908127 6) Surgery vs. radiation vs. active surveillance: https://www.nejm.org/doi/full/10.1056/NEJMoa1606220

Chris and Jonathan speak to Anne Borden, Amanda Seigler, and Melissa Eaton who are campaigning against phony autism cures.   0:55 Alternative treatments for autism and why they exist 3:28 Going undercover on Facebook 5:00 MMS or the bleach cure 11:00 The pushback against activism 12:31 How social media companies have responded 14:10 Chelation therapy 23:45 Pro-science celebrities 26:00 Special diets 27:40 The medical community and applied behaviour analysis (ABA) 34:24 Humane interventions for autism   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   The petition against toxic “cures” in the US: https://www.change.org/p/united-states-congress-bring-legislation-against-toxic-cures-in-the-united-states-eaa2029c-36c3-4d4d-97ca-08f0a06e1f84   Links: 1) Autistic Self Advocacy Network: https://autisticadvocacy.org 2) Foundations for Divergent Minds: https://www.divergentminds.org 3) Autistic Inclusive on Facebook: https://www.facebook.com/autisticinclusivemeets/?eid=ARCCGmkCnb1ATBL515bePaUSQV_8izJNK01wQ1Ku9NXFjiD2a6Cs60-92t8dG3_WXfB1pUWkF23ArXuA&timeline_context_item_type=intro_card_work&timeline_context_item_source=100008073797054&fref=tag   Social: 1) Melissa Eaton on Facebook: https://www.facebook.com/melissa.eaton.98 2) Amanda Seigler on Facebook: https://www.facebook.com/amanda.seigler.3517 3) Anne Borden on Twitter: https://twitter.com/AgainstCures 4) Anne’s podcast: http://noncompliantpodcast.com

Breast cancer screening: self-exams, mammograms, ductal carcinoma in situ, Angelina Jolie // The book “Bottle of Lies” and the safety of generic drugs // When cancer research misses its target   * Vox pop by Morgan Sweeney * Jingle by Joseph Hackl of Voodoo Jazz * Additional music by Seth Donnelly and Kevin MacLeod of Incompetech.com. * Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra.   To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/.   Patrons get a bonus show on Patreon called “Digressions”! Check it out!   References: 1) The Malmö Study: https://www.ncbi.nlm.nih.gov/pubmed/3142562 2) The Canadian National Breast Screening Study: https://www.bmj.com/content/348/bmj.g366 3) The 2012 Lancet Study: https://www.ncbi.nlm.nih.gov/pubmed/23117178 4) The Cochrane Collaboration Review: https://www.cochrane.org/CD001877/BREASTCA_screening-for-breast-cancer-with-mammography

A questionable plate of spaghetti produces something unexpected: Chris' teddy bear can now speak! Once the acid trip wears off, Jonathan and Chris discuss study aid drugs or "nootropics", like Ritalin being used by 12-year-olds to get better grades. Do these stimulants work and are there side effects? They also discuss Adderall, racetams, omega-3s, ginseng, gingko biloba, and the cocaine of Silicon Valley bros, modafinil. Also: a comprehensive look at the fluoride-and-IQ study that came out and should certain populations all get a combo pill regardless of whether individuals need it? Vox pop by Ada McVean of the McGill Office for Science and Society.   Jingle by Jillian Correia of Roctavio Canada. Additional music by Seth Donnelly, Epidemic Sound, and Kevin MacLeod. Theme music: "Troll of the Mountain Swing" by the Underscore Orkestra. To contribute to The Body of Evidence, go to our Patreon page at: http://www.patreon.com/thebodyofevidence/. Patrons get a bonus show on Patreon called "Digressions"! Check it out! LINKS: The Body of Evidence video on ear candles: https://www.youtube.com/watch?v=-GfunNxHHkw Fluoride and IQ study: https://jamanetwork.com/journals/jamapediatrics/fullarticle/2748634 REFERENCES: FDA warning letter against nootropics: https://www.fda.gov/inspections-compliance-enforcement-and-criminal-inve... Ritalin and academic performance: https://www.ncbi.nlm.nih.gov/pubmed/29353323 https://www.theatlantic.com/health/archive/2013/06/study-ritalin-doesnt-... Health Canada warning on modafinil https://healthycanadians.gc.ca/recall-alert-rappel-avis/hc-sc/2019/70201... Cochrane reviews on omega-3s, gingko, and ginseng:https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007986.pub2/...https://www.cochrane.org/CD003120/DEMENTIA_there-is-no-convincing-eviden...https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD007769.pub2/...