In the Know with Amol Sarva

Amol Sarva
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Jul 10, 2023 • 50min

Matt Kaeberlein on which longevity supplements might really work, and which don’t

Professor Matt Kaeberlein is an outspoken proponent of rapamycin, and pretty skeptical about virtually all the other interventions people talk most about. Here he lays out a pretty complete and persuasive model for why and how aging happens at all, and why some approaches are most likely to work.
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Dec 12, 2022 • 39min

Nir Barzilai on the genes of centenarians and some nuance on metformin

A rare MD at the cutting edge of the longevity field, Dr. Barzilai heads the Institute for Longevity Research at Einstein. We cover his unique contributions, especially the currently buzzy topic of metformin, as well as his work on the genetic luck of centenarians.
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Dec 12, 2022 • 36min

Jean Herbert on regenerating the brain in the lab

One of the more incredible research programs in longevity is regeneration: rebuilding and replacing failing organs with lab-grown cells. Jean Herbert at Einstein is working on regenerating your brain.
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Nov 29, 2022 • 53min

James Peyer from Cambrian Biosciences and Apollo Health Ventures tells us how to play longevity to win

This founder has been part of so many of the exciting longevity startups, investments, and discussions that you simply must understand the world the way he sees it before taking a view about life extension. In this episode, you will.
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Nov 10, 2022 • 47min

Aubrey de Grey, the longevity OG, gives us a peek into the early days of the cult of living forever

Longevity superstar alert. A deep dive with one of the most recognized and longest-serving visionaries of longevity world. After recording this episode, friends pointed out that I didn't cover big important parts of personal history that are covered here: https://en.wikipedia.org/wiki/Aubrey_de_Grey
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Nov 6, 2022 • 48min

Vincere Bio’s computer model for solving Parkinson’s with the cofounders Spring Behrouz and Andy Lee

The easy way to attack Parkinson's? A neuron-by-neuron model of the brain.
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Sep 8, 2022 • 24min

Altos Labs’ Morgan Levine on how to measure biological age and why she left Yale

Cellular rejuvenation is in the house on this episode, and fundamental research on the processes far beneath the surface of your typical aging research. And a little peek into the billionaire-backed mega-project happening at Altos.
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Sep 1, 2022 • 45min

Bjoern Schumacher’s research on cellular damage, and that incredible longevity-busting work on worms

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Aug 25, 2022 • 44min

Professor Richard Miller’s experiments on all the life extending elixirs

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Aug 18, 2022 • 47min

Reason of Repair Biotechnologies on reversing cellular aging

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