In the Know with Amol Sarva

We analyzed the 1,000s of companies we're watching and investing in at LifeX. We looked at every update email from every CEO and every conversation notes from every team member. And we made hits outlook for the year ahead, automagically. (Excuse robo-typos.) Enjoy!

We synthesized the dozens of outlook reports from Wall Street analysts on health, biopharma, and related trends. Listen in to Amolbot (an automated Amol) and co-hosts.

We synthesized the dozens of outlook reports from Silicon Valley observers of techbio for AI x Health startups and trends. Listen in to Amolbot (an automated Amol) and co-hosts.

Dr. B is an expert on gut health and shouting its power from the rooftops, both in his practice and writings but also through the company Zoe where he is US medical director. Some interesting news about coffee in this one. Metabolic Health is the biggest medical breakthrough of the moment. Dive in!

The journey from food through digestion to your liver to energy stores and metabolizing work is the obsession of sports science - and hugely relevant to metabolic health overall. Let's get this perspective from research professor Derek Huffman at Einstein Medicine in New York. Dive into metabolic health!

The different foods we eat and how they interact make a huge difference in disease progression, weight, and everything else. Dr. Jeff Alfonsi is a practicing physician for years, and chief medical officer of RxFoods which is designed to identify what you are eating and how to get better results. Metabolic Health is the biggest medical breakthrough of the moment. Dive in.

Let's understand an overlooked dimension of the weight loss revolution underway -- the microbes in the digestive system themselves, potentially where GLP-1s come from in the first place. Duke's gut biome expert Maya Kaelberer gives us a guide. Metabolic Health is the biggest medical breakthrough of the moment. Dive in!

Metabolic Health is the biggest medical breakthrough of the moment Let's understand the cellular mechanisms and some of the most promising and widely used drugs in the world with one of the foremost researchers in the field, Matt Kaeberlein, formerly of University of Washington and now founder of longevity company Optispan

Metabolic Health is the biggest medical breakthrough of the moment Mapping all the ways the GLP-1 drugs like Ozempic do and might work means we need to understand the biome and the efficacy of surgical interventions. We talk to Professor Randy Seeley who directs University of Michigan's Nutrition Obesity Research Center

Metabolic Health is the biggest medical breakthrough of the moment Dr. John Buse has been at the forefront of diabetes research and endocrinology since before the first GLP-1 results started to become known. He studies the body's systems that seem to be at the core of how Ozempic and diabetes operate -- let's learn about the endocrine system and map out these system-level interactions