

Hypertrophy Past and Present
Chris Beardsley and Jake Doleschal
A deep dive into the science of muscle growth. Hosted by Chris Beardsley and Jake Doleschal, this podcast explores hypertrophy training through the lens of pre-steroid era bodybuilding and modern muscle physiology.
Episodes
Mentioned books

Oct 27, 2025 • 1h 6min
023 Fatigue accumulation and what to do about it.
In this episode of Hypertrophy: Past and Present, Jake and Chris unpack a Silver-Era routine passed from 1950 Mr America John Farbotnik to Gene Mozee at a time where high volume plans were taking over bodybuilding. From there they go deep into accumulating fatigue, how excitation–contraction coupling failure, muscle damage, and supraspinal CNS fatigue interact across sessions, why exercise novelty and split design can make this worse, and how to calculate and clear your “fatigue debt” without losing muscle.Key topics include:John Farbotnik full body routineBack-off sets: why back-offs add soreness but little stimulusThe three post-workout fatigue mechanisms (ECC failure, muscle damage, supraspinal CNS): timelines, interactions, and accumulationHow swapping exercises can re-hit damaged fibres and accumulate fatiguePractical programming, typical recovery times, and fatigue-debt math

12 snips
Oct 19, 2025 • 58min
022 How intra-workout carbohydrates reduce supraspinal CNS fatigue
Explore the fascinating world of Steve Reeves' classic workout routine, emphasizing orange juice and honey as a training staple. Discover the surprising science behind carbohydrate mouth-rinsing and its role in combatting supraspinal CNS fatigue during strength training. Learn how carbs can enhance performance differently than creatine and how perceived effort influences motor unit recruitment. Plus, practical tips on incorporating carbohydrate strategies into your regimen to maximize your gains!

11 snips
Oct 13, 2025 • 1h 8min
021 Why Counting “Half Sets” for Secondary Muscles Doesn't Make Sense
Jake and Chris delve into Dick DuBois' 1954 full-body training routine, highlighting unique exercises like behind-the-neck presses. They tackle the flawed idea of 'half sets' for secondary muscles, explaining how muscle growth responses differ between beginners and advanced lifters. The duo explores the mechanics of multi-joint lifts and how to steer them for specific muscle targeting. Additionally, they discuss the evolution of training styles, arguing that full-body workouts were once the standard before the rise of splits.

11 snips
Oct 6, 2025 • 1h 21min
020 How to program a muscle specialisation phase
The hosts dive into Peary Rader's classic leg routine, adjusting it for modern training needs. They discuss programming strategies to optimize muscle specialization while integrating it into existing plans, emphasizing the importance of compound lifts for overall growth. Key topics include the value of knee-dominant squats for quad development and balancing different lift types. The conversation also covers how to handle training frequency, session limits, and the rise of science-driven methods among younger lifters.

13 snips
Sep 29, 2025 • 1h 21min
019 Cluster Sets – How they work and how to use them
Exploring the 20-rep breathing squat, the hosts highlight its significance in Reg Park's training. They explain cluster sets and how they differ from rest-pause and drop sets, diving into fatigue mechanisms such as spinal and metabolite fatigue. Discover the advantages of clusters, especially when using heavy loads, and gain insights on practical programming strategies. From selecting the right exercises to monitoring progress, the discussion equips listeners with tools to optimize their workouts while emphasizing simplicity in programming.

19 snips
Sep 22, 2025 • 1h 24min
018 Pauses, Stretching, and Partials
Explore Reg Park’s classic calf specialization routine and discover the intricate differences between straight-leg and bent-leg calf exercises. Delve into the science of pause fatigue, unraveling metabolite versus calcium-related fatigue mechanisms. Learn why static stretching and active contractions serve different purposes in training. Practical insights reveal how to optimize muscle leverage with pauses and partials for effective results. A practical calf training plan ties it all together, ensuring gains for both the gastroc and soleus.

13 snips
Sep 15, 2025 • 1h 22min
017 Exercise Selection - How to pick the exercises needed to maximally develop a muscle
Dive into the world of exercise selection, exploring the historical impact of Sig Klein’s routines. Discover how neuromechanical matching affects muscle recruitment and why some workouts need more variety than others. The discussion unveils unique exercises for the quadriceps and triceps, emphasizing their effectiveness. Learn about the significance of unilateral work in maximizing muscle activation and the complexities behind muscle anatomy. Improve your training strategy with insights on optimal exercise choices for targeted growth and performance!

10 snips
Sep 8, 2025 • 1h 14min
016 Training Splits - Why upper/lower, torso/limbs, push/pull, and other split routines face the same problem
Dive into the historical roots of bodybuilding training and discover the transition from full-body routines to splits. Explore the fascinating influence of anabolic steroids on muscle growth, especially in the neck and trapezius areas. Unpack the science behind muscle fatigue and its impact on training splits, highlighting why back-to-back training days can diminish effectiveness. Gain insights on optimizing workout frequency and exercise selection to combat central nervous system fatigue, ultimately enhancing performance and muscle growth.

10 snips
Sep 1, 2025 • 1h 12min
015 Training Frequency - Why 3x per week beats 2x even if MYOPS is still elevated
Dive into the world of vintage bodybuilding with insights on Sig Klein's groundbreaking A/B full body routine. Discover the intricate role of myofibrillar protein synthesis in muscle growth and why training three times a week trumps two, despite elevated synthesis. The hosts explore historical training methods, revealing their modern relevance, and compare training programs for optimizing hypertrophy. A fascinating discussion on how workout frequency impacts muscle development awaits, shedding light on effective training principles.

19 snips
Aug 25, 2025 • 1h 15min
014 Training Frequency - What the long-term studies actually show
Discover the intriguing world of bodybuilding history with insights on Floyd Page’s 1952 workout routine. Dive into the nuances of training frequency and how it influences muscle growth. The discussion reveals why hitting the gym three times a week is often more beneficial than once a week. Unpack the complexities of research on hypertrophy, and learn about the challenges in analyzing muscle measurement techniques. The speakers also advocate for critical thinking and source verification in fitness to cut through the misinformation surrounding training practices.


