

Hypertrophy Past and Present
Chris Beardsley and Jake Doleschal
A deep dive into the science of muscle growth. Hosted by Chris Beardsley and Jake Doleschal, this podcast explores hypertrophy training through the lens of pre-steroid era bodybuilding and modern muscle physiology.
Episodes
Mentioned books

6 snips
Nov 23, 2025 • 1h 13min
027 Are 4 reps optimal?! New study: stimulating reps vs volume load
Dive into the contrasting training philosophies of Bill Pearl from 1967, highlighting his high-volume six-day split that paved the way for modern routines. Discover how anabolic steroids transformed recovery and training volume, breaking traditional feedback loops. A new study uncovers that both heavy and light loads yield similar hypertrophy, challenging the volume load hypothesis. Join the discussion on practical programming for beginners versus advanced lifters and the real-world challenges of implementing these findings.

9 snips
Nov 16, 2025 • 1h 20min
026 How does insufficient sleep affect hypertrophy / atrophy?
Explore the intriguing world of Bill Pearl's 1957 full-body routine and its connection to the evolution of bodybuilding. Discover how insufficient sleep can trigger muscle atrophy through stress responses and the role of glucocorticoids. Learn why natural lifters face significant muscle loss when dieting while sleep-deprived, unlike enhanced athletes. Gain practical tips on adjusting training strategies during periods of poor sleep and understand the importance of tackling sleep issues before dieting. A fascinating mix of science and practical advice awaits!

10 snips
Nov 9, 2025 • 56min
025 How does insufficient sleep affect training?
This discussion dives into Bob Hoffman’s full-body hypertrophy program, analyzing its relevance today. The hosts explore how insufficient sleep impacts performance, detailing the differences between sleep deprivation, restriction, and cumulative sleep debt. You'll learn that sleep loss affects coordination and motor learning more than hypertrophy, and find practical tips for adjusting workouts after poor sleep, including opting for single sets. The conversation also highlights the risks of missed training sessions and their long-term impact on muscle progress.

14 snips
Nov 2, 2025 • 1h 4min
024 Training, hypertrophy, and recovery for older people
Explore the nuanced world of training for older lifters, focusing on recovery and programming. Discover insights on how heavier loads can reduce workout fatigue and maintain muscle with minimal volume. Learn about the importance of isometrics for safe motor unit recruitment and practical exercise selection strategies. The discussion reveals how accumulated fatigue impacts progress and highlights adjustments needed as recovery capacity declines with age. Perfect for those seeking to optimize their training approach in later life.

13 snips
Oct 27, 2025 • 1h 6min
023 Fatigue accumulation and what to do about it.
Jake and Chris delve into a fascinating Silver-Era bodybuilding routine and discuss how fatigue accumulates over time. They explore three key post-workout fatigue mechanisms: excitation–contraction coupling failure, muscle damage, and central nervous system fatigue. The hosts explain why back-off sets can lead to soreness without significant benefits and the risks of exercise novelty on fatigue levels. Practical programming tips and strategies for managing fatigue debt are shared, which can help maximize gains while ensuring adequate recovery.

12 snips
Oct 19, 2025 • 58min
022 How intra-workout carbohydrates reduce supraspinal CNS fatigue
Explore the fascinating world of Steve Reeves' classic workout routine, emphasizing orange juice and honey as a training staple. Discover the surprising science behind carbohydrate mouth-rinsing and its role in combatting supraspinal CNS fatigue during strength training. Learn how carbs can enhance performance differently than creatine and how perceived effort influences motor unit recruitment. Plus, practical tips on incorporating carbohydrate strategies into your regimen to maximize your gains!

11 snips
Oct 13, 2025 • 1h 8min
021 Why Counting “Half Sets” for Secondary Muscles Doesn't Make Sense
Jake and Chris delve into Dick DuBois' 1954 full-body training routine, highlighting unique exercises like behind-the-neck presses. They tackle the flawed idea of 'half sets' for secondary muscles, explaining how muscle growth responses differ between beginners and advanced lifters. The duo explores the mechanics of multi-joint lifts and how to steer them for specific muscle targeting. Additionally, they discuss the evolution of training styles, arguing that full-body workouts were once the standard before the rise of splits.

11 snips
Oct 6, 2025 • 1h 21min
020 How to program a muscle specialisation phase
The hosts dive into Peary Rader's classic leg routine, adjusting it for modern training needs. They discuss programming strategies to optimize muscle specialization while integrating it into existing plans, emphasizing the importance of compound lifts for overall growth. Key topics include the value of knee-dominant squats for quad development and balancing different lift types. The conversation also covers how to handle training frequency, session limits, and the rise of science-driven methods among younger lifters.

13 snips
Sep 29, 2025 • 1h 21min
019 Cluster Sets – How they work and how to use them
Exploring the 20-rep breathing squat, the hosts highlight its significance in Reg Park's training. They explain cluster sets and how they differ from rest-pause and drop sets, diving into fatigue mechanisms such as spinal and metabolite fatigue. Discover the advantages of clusters, especially when using heavy loads, and gain insights on practical programming strategies. From selecting the right exercises to monitoring progress, the discussion equips listeners with tools to optimize their workouts while emphasizing simplicity in programming.

19 snips
Sep 22, 2025 • 1h 24min
018 Pauses, Stretching, and Partials
Explore Reg Park’s classic calf specialization routine and discover the intricate differences between straight-leg and bent-leg calf exercises. Delve into the science of pause fatigue, unraveling metabolite versus calcium-related fatigue mechanisms. Learn why static stretching and active contractions serve different purposes in training. Practical insights reveal how to optimize muscle leverage with pauses and partials for effective results. A practical calf training plan ties it all together, ensuring gains for both the gastroc and soleus.


