Join Weiwei Xue, a pioneering researcher in cryopreservation techniques for human brain tissue, alongside Hao Chen, who focuses on brain organoids, and Brian Callahan, an expert on personality changes post-transplant. They discuss breakthrough cryopreservation methods that could change neuroscience. Fascinatingly, they delve into how organ transplant recipients often experience shifts in personality, possibly influenced by their donors. The conversation also touches on the impact of azole fungicides on combating fungal diseases, highlighting new mechanisms of action.