Todd Roberts and Lacey Ann Luna, co-founders of Intertwining Medicines, share their deep-rooted experiences in the Shipibo ayahuasca tradition. They explore transformative journeys of healing, particularly during the COVID pandemic, and highlight the challenges of facilitating ceremonies. The duo discusses the balance between genuine spiritual callings and ego-driven desires, the complexities of morality, and the significance of integrity in healing practices. Their insights into plant intelligence and cultural respect offer a profound perspective on the evolving landscape of ayahuasca retreats.