Thomas Vierbuchen

Dr. Thomas Vierbuchen, an Assistant Professor at Memorial Sloan Kettering Cancer Center, explores the intricacies of neural development through pluripotent stem cells. He discusses the advantages of 2D cultures versus complex organoids for research reproducibility. Vierbuchen recounts the surprising journey of direct reprogramming from fibroblasts to neurons and the challenges faced in translating these techniques to human cells. He also highlights the importance of understanding embryogenesis and the intriguing question of how organs determine their size.