Suzanne Morin, a Professor of Medicine at McGill University and expert on osteoporosis, joins JAMA Deputy Editor Mary McDermott to discuss this critical health issue. They delve into the alarming statistics, noting that 1 in 3 women and 1 in 5 men over 50 experience osteoporotic fractures. Risk factors and screening are vital, especially for those with prior fractures. Morin also sheds light on treatment options, including medications like bisphosphonates, and the emerging anabolic therapies that could significantly improve outcomes for high-risk patients.