In this milestone discussion, physicist and computational biologist Andrew Steele, author of 'Ageless,' explores the science behind longevity supplements. He delves into popular compounds like NMN and spermidine, questioning their true effectiveness in extending life. Listener Solly Milton highlights the buzz around biohackers aiming to reverse aging, prompting a critical look at these claims. The conversation critiques the antioxidant myth and suggests a balanced approach to health, emphasizing evidence-based practices over costly supplements.