Dr. Jerry Rosenbaum, a founding director and author in psychedelic research, teams up with Sharmin Ghaznavi, MD, Ph.D., a psychiatric expert in cognitive neuroscience. They delve into the fascinating relationship between rumination and the default mode network. Discussing how psychedelics like psilocybin can help disrupt negative thought patterns, they highlight groundbreaking neuroimaging techniques, including hyperscanning, to strengthen the therapist-patient bond. Their insights explore the evolving therapeutic landscape and the potential of psychedelics in treating mental health challenges.