Seema Amble

Partner on the apps investing team focusing on enterprise AI; discusses enterprise orchestration, context extraction from documents and human actions, and coordinated multi-agent systems for Fortune 500 companies.

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Dec 23, 2025 • 22min

Big Ideas 2026: The Enterprise Orchestration Layer

Seema Amble, a partner on the enterprise AI investing team, discusses how Fortune 500 companies can leverage coordinated multi-agent systems for efficiency. Angela Strange, an expert in financial services, advocates for the replacement of legacy systems with AI-native platforms that unify data. Alex Immerman introduces 'multiplayer mode,' where humans and agents collaborate through trust rules. David Haber emphasizes the importance of AI that reinforces business models, highlighting how proprietary outcomes data can create competitive advantages.

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