Big Ideas 2026: The Enterprise Orchestration Layer

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Dec 23, 2025

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Seema Amble, a partner on the enterprise AI investing team, discusses how Fortune 500 companies can leverage coordinated multi-agent systems for efficiency. Angela Strange, an expert in financial services, advocates for the replacement of legacy systems with AI-native platforms that unify data. Alex Immerman introduces 'multiplayer mode,' where humans and agents collaborate through trust rules. David Haber emphasizes the importance of AI that reinforces business models, highlighting how proprietary outcomes data can create competitive advantages.

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INSIGHT

AI As The Enterprise Orchestration Layer

AI will become an orchestration layer that coordinates agents across departments and tools.
This shifts workflows from isolated tools to coordinated systems that plan, analyze, and execute work.

ADVICE

Build A Context Layer From Tacit Knowledge

Extract tacit knowledge from documents and human actions to create a shared context layer.
Measure agents with KPIs and eval functions and adjust their objective functions when metrics conflict.

INSIGHT

Fortune 500s Are Primed For Orchestration

Fortune 500s have dense, siloed data and slow change processes that make them prime targets for agent orchestration.
A context layer can accelerate large-scale changes like ERP or procurement rollouts across geographies.

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AI is becoming the orchestration layer inside the enterprise.

In this episode of Big Ideas 2026, we explore the shift from isolated AI copilots to coordinated multi-agent systems that plan, analyze, and execute work across teams and tools. This is not a new feature, but a new way workflows run inside large organizations.

You will hear from Seema Amble on context extraction and coordinated agent teams, Angela Strange on why unified data and parallel workflows accelerate core replacement, Alex Immerman on multiplayer AI and execution boundaries, and David Haber on what makes these systems commercially defensible.

Together, these perspectives define the enterprise orchestration layer: not a chatbot and not a standalone tool, but a coordinated system of agents that runs the workflow and delivers real outcomes across the business.