In this episode, my guest is Robin Carhart-Harris, PhD, distinguished professor of neurology and psychiatry at the University of California, San Francisco. He is one of leading researchers in the study of how psychedelics such as psilocybin, LSD and DMT can change the human brain and in doing so, be used to successfully treat various mental health challenges such as major depression, anorexia, obsessive-compulsive disorder (OCD) and addiction. He explains how psilocybin induces sustained changes in adaptive brain wiring and cognition. We discuss the key components of safe and effective psychedelic journeys, the role of hallucinations, the use of eye-masks to encourage people to “go internal,” and music, as well as what effective therapist support consists of before, during and after the session (also known as integration). We discuss micodosing vs. macrodosing and how researchers control for placebo effects in psychedelic research. We also discuss the current legal landscape around psychedelic therapies. Psychedelic therapies are fast emerging as powerful and soon-to-be mainstream treatments for medical health disorders, but they are not without their risks. As such, this episode ought to be of use to anyone interested in brain plasticity, mental health, psychology or neuroscience.For the full show notes, visit hubermanlab.com.Thank you to our sponsorsAG1 (Athletic Greens): https://athleticgreens.com/hubermanLMNT: https://drinklmnt.com/hubermanWaking Up: https://www.wakingup.com/hubermanMomentous: https://www.livemomentous.com/hubermanThe Brain Body Contracthttps://hubermanlab.com/tourTimestamps(00:00:00) Dr. Robin Carhart-Harris(00:02:28) Sponsors: LMNT & Waking Up(00:05:41) The Brain-Body Contract(00:06:31) Origin of the Word: “Psychedelics”; Pharmacology(00:12:05) Psychedelics & Revealing the Unconscious Mind, Psychotherapy(00:17:32) Microdosing(00:26:08) Psilocybin vs. Magic Mushroom Doses(00:28:28) “Psychedelic-Therapy”, Music(00:31:13) Sponsor: AG1(00:36:26) Psychedelic Journey: “Trust, Let Go, Be Open”(00:43:01) Negative Emotions, Fear & Psychedelics(00:46:21) Global Functional Connectivity, Serotonin 2A Receptor; Subjective Experiences(00:52:33) Pharmacology: Therapeutics without Psychedelic Effects; SSRIs(00:58:45) Psilocybin & Depression; Long-Term Effects: Connectivity & Neuroplasticity(01:10:26) Psilocybin Therapy & Anorexia(01:12:56) Integration Phase & Psychedelic-Therapy; Meditation(01:19:50) First-Time Psychedelic Use, “Entropic Brain Effect”, Neuroplasticity, Cognition(01:30:16) Fibromyalgia & Psychedelic Treatment; MDMA Therapy & “Inner Healer”(01:38:55) Placebo Response & Psychedelic Therapy(01:41:39) LSD & Psychedelic-Therapy, Micro-Dose(01:48:19) Combination Psilocybin-MDMA Therapy(01:56:06) DMT “Rocketship” & Serotonin 2A Receptors; Ibogaine(02:01:04) “Ego Dissolution”, Cocaine vs. Psychedelics; Relapses(02:12:26) Psychedelics & Legal Landscape; Decriminalization(02:17:54) MDMA, Trauma & Clinical Trials; Future Regulatory (FDA) Approval?(02:23:25) Psilocybin & Current Clinical Trials(02:28:41) Mental Health & Psychedelic Treatment, Safeguards, Paradigm Shift(02:34:39) Zero-Cost Support, YouTube Feedback, Spotify & Apple Reviews, Sponsors, Momentous, Social Media, Neural Network NewsletterTitle Card Photo Credit: Mike BlabacDisclaimer

Dr. Peterson's extensive catalog is available now on DailyWire+: https://utm.io/ueSXhDr Jordan B Peterson and Dr. Robin Carhart-Harris delve into the world of psychedelic research, their utility in therapy, and the impact they can have on neuroticism. They also explore broader aspects of psychopathology, brain imaging, optimized play, and the way trauma can warp our perspectives of the world. Robin is the Ralph Metzner Distinguished Professor in Neurology and Psychiatry and Director of Neuroscape’s Psychedelics Division at the University of California, San Francisco. He moved to Imperial College London in 2008 after obtaining a PhD in Psychopharmacology from the University of Bristol. Robin has designed human brain imaging studies with LSD, psilocybin, MDMA and DMT, and several clinical trials of psilocybin therapy for severe mental illnesses. Robin founded the Centre for Psychedelic Research at Imperial College London in April 2019, was ranked among the top 31 medical scientists in 2020, and in 2021, was named in TIME magazine’s ‘100 Next’ – a list of 100 rising stars shaping the future. His research is creating system-level change in mental health care.  - Sponsors - Express VPN: Get 3 Months FREE of ExpressVPN: https://expressvpn.com/jordan Birch Gold: Text "JORDAN" to 989898 for a FREE Goldback with every $5000 purchase, when you convert an existing IRA or 401k into a precious metals IRA with Birch Gold by December 22nd. Black Rifle Coffee: Get 10% off your first order or Coffee Club subscription with code JORDAN: https://www.blackriflecoffee.com/ Exodus 90: Is it time for your Exodus? Find resources to prepare at https://exodus90.com/jordan.   - Links -  For Dr. Carhart-Harris: Twitter: https://twitter.com/RCarhartHarris Website:  https://neuroscape.ucsf.edu/profile/robin-carhart-harris/   - Chapters - (0:00) Coming Up(1:00) Intro(2:50) Implicit learning(7:52) Tuned perceptions, warped vantage points(12:00) Rebirth, rapid new learning(16:00) Alcoholism, unlearning pain(20:22) Neuroticism, Freud, and the disconnect(24:00) Cascading depression(30:10) Functional depression(35:30) The source of psychopathology(46:48) The psychedelic experience(49:47) Genetic mutation, error correction(53:30) Micro and macro environments(56:33) The multitude within(58:39) Pageau, optimized play(1:04:00) When play is absent from the system(1:07:25) Depth of play, levels of engagement(1:09:55) Local minima(1:13:29) Psychedelics and antidepressants(1:17:40) Creative surging under influence(1:21:30) Every benefit has a cost(1:23:32) Terrance and Dennis McKenna, false positives(1:26:15) Paranoid Schizophrenia(1:29:26) The feeling of confidence vs. uncertainty(1:33:33) Exposure therapy, building up bravery(1:35:00) Brain imaging, mapping experience(1:38:40) Entropic brain principle(1:40:00) Between order and chaos, Marduk(1:44:16) Signatures of criticality, the Alpha Rhythm       // SUPPORT THIS CHANNEL //Newsletter: https://mailchi.mp/jordanbpeterson.co...Donations: https://jordanbpeterson.com/donate // COURSES //Discovering Personality: https://jordanbpeterson.com/personalitySelf Authoring Suite: https://selfauthoring.comUnderstand Myself (personality test): https://understandmyself.com // BOOKS //Beyond Order: 12 More Rules for Life: https://jordanbpeterson.com/Beyond-Order12 Rules for Life: An Antidote to Chaos: https://jordanbpeterson.com/12-rules-...Maps of Meaning: The Architecture of Belief: https://jordanbpeterson.com/maps-of-m... // LINKS //Website: https://jordanbpeterson.comEvents: https://jordanbpeterson.com/eventsBlog: https://jordanbpeterson.com/blogPodcast: https://jordanbpeterson.com/podcast // SOCIAL //Twitter: https://twitter.com/jordanbpetersonInstagram: https://instagram.com/jordan.b.petersonFacebook: https://facebook.com/drjordanpetersonTelegram: https://t.me/DrJordanPetersonAll socials: https://linktr.ee/drjordanbpeterson #JordanPeterson #JordanBPeterson #DrJordanPeterson #DrJordanBPeterson #DailyWirePlus #podcast

Sam Harris speaks with Jeannie Fontana and Robin Carhart-Harris about the TREAT Initiative in California and the growing promise of psychedelics for mental health care. They discuss drug discovery, PTSD therapy, approval process, high costs of studies, effects on the brain, and the topic of organized religion.

Guests Amanda Feilding, a pioneer in psychedelic research, Robin Carhart-Harris, creator of the 'entropic brain' theory, and renowned neuroscientist Christof Koch delve deep into consciousness and psychedelics. They discuss psilocybin's transformative effects and how it can aid in healing trauma. Christof shares his journey exploring 5-MeO-DMT, while Amanda reflects on shifting societal perceptions of psychedelics. Together, they challenge conventional neuroscience, revealing the profound implications these substances have on understanding consciousness.

This episode features a panel that I moderated in front of a standing-room-only crowd at the Milken Institute's Global Conference 2019. It includes a great overview of psychedelic science, investing opportunities, anecdotal personal benefits, legal challenges, and much more. I think it’s one of the more comprehensive panels ever done on the subject. Here are the participants:Matthew Johnson — Principal Investigator, Johns Hopkins Psychedelic Research UnitAyelet Waldman — Author, A Really Good Day: How Microdosing Made a Mega Difference in My Mood, My Marriage, and My LifeRobin Carhart-Harris — Head of Psychedelic Research, Centre for Psychedelic Research, Department of Brain Sciences, Imperial College LondonChristian Angermayer — Founder, Apeiron Investment Group and ATAI Life SciencesPlease enjoy!***If you enjoy the podcast, would you please consider leaving a short review on Apple Podcasts/iTunes? It takes less than 60 seconds, and it really makes a difference in helping to convince hard-to-get guests. I also love reading the reviews!For show notes and past guests, please visit tim.blog/podcast.Sign up for Tim’s email newsletter (“5-Bullet Friday”) at tim.blog/friday.For transcripts of episodes, go to tim.blog/transcripts.Discover Tim’s books: tim.blog/books.Follow Tim:Twitter: twitter.com/tferriss Instagram: instagram.com/timferrissFacebook: facebook.com/timferriss YouTube: youtube.com/timferrissPast guests on The Tim Ferriss Show include Jerry Seinfeld, Hugh Jackman, Dr. Jane Goodall, LeBron James, Kevin Hart, Doris Kearns Goodwin, Jamie Foxx, Matthew McConaughey, Esther Perel, Elizabeth Gilbert, Terry Crews, Sia, Yuval Noah Harari, Malcolm Gladwell, Madeleine Albright, Cheryl Strayed, Jim Collins, Mary Karr, Maria Popova, Sam Harris, Michael Phelps, Bob Iger, Edward Norton, Arnold Schwarzenegger, Neil Strauss, Ken Burns, Maria Sharapova, Marc Andreessen, Neil Gaiman, Neil de Grasse Tyson, Jocko Willink, Daniel Ek, Kelly Slater, Dr. Peter Attia, Seth Godin, Howard Marks, Dr. Brené Brown, Eric Schmidt, Michael Lewis, Joe Gebbia, Michael Pollan, Dr. Jordan Peterson, Vince Vaughn, Brian Koppelman, Ramit Sethi, Dax Shepard, Tony Robbins, Jim Dethmer, Dan Harris, Ray Dalio, Naval Ravikant, Vitalik Buterin, Elizabeth Lesser, Amanda Palmer, Katie Haun, Sir Richard Branson, Chuck Palahniuk, Arianna Huffington, Reid Hoffman, Bill Burr, Whitney Cummings, Rick Rubin, Dr. Vivek Murthy, Darren Aronofsky, and many more.See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Dr. Robin Carhart-Harris discusses psychedelics, plasticity, set and setting in research. Talks about origins, early LSD studies, potential for pain management, fibromyalgia, anorexia, and therapeutic benefits of psychedelics. Explores cultural impact of MDMA on nightclub culture.

Robin Carhart-Harris, a neuroscientist and psychopharmacologist at UCSF, dives into the fascinating world of psychedelics and their impact on the brain. He unpacks the 'entropic brain' hypothesis, revealing how psychedelics increase brain entropy, leading to heightened consciousness. The discussion covers the therapeutic potential of substances like psilocybin for conditions such as PTSD and depression, and critiques current regulatory hurdles. Insights into brain connectivity and the complexities of consciousness make this a thought-provoking exploration.

Neuroscientist Robin Carhart-Harris discusses psychedelics' therapeutic potential and founding a center for psychedelic research. Topics include LSD experiences, molecular impact on the brain, benefits for mental health, transformative potential in daily life, and exploration of spirituality.

Psychedelic researcher Robin Carhart-Harris discusses the therapeutic benefits of psychedelics and their impact on the unconscious mind. They explore the debate between neurorealism and the cognitive fallacy, blinding integrity in psychedelic trials, and the relationship between potential information and complexity theory. The podcast also delves into the psychedelic experience, insights gained from psychedelic trips, the potential of video therapy, harm reduction education, and ongoing projects in psychedelic research.

The Convention on Psychotropic Substances was a 1971 United Nations treaty that placed strong restrictions on the use of psychedelic drugs — not only on personal use, but medical and scientific research as well. Along with restrictions placed by individual nations, it has been very difficult for scientists to study the effects of psychedelics on the brain, despite indications that they might have significant therapeutic potential. But this has gradually been changing, and researchers like Robin Carhart-Harris have begun to perform controlled experiments to see how psychedelics affect the brain, and what positive uses they might have. Robin and I talk about how psychedelics work, how they can help with conditions from addiction to depression, and how they can help people discover things about themselves.Support Mindscape on Patreon.Robin Carhart-Harris received his Ph.D. in psychopharmacology from the University of Bristol. He is currently the Director of the Centre for Psychedelic Research in the Department of Brain Sciences at Imperial College London, and holds an honorary position at the University of Oxford. His research involves functional brain imaging studies with psilocybin (magic mushrooms), LSD, MDMA (ecstasy) and DMT (ayahuasca), plus a clinical trial of psilocybin for treatment-resistant depression.Web siteCentre for Psychedelic ResearchGoogle Scholar pageTalk on Psychedelics: Lifting the VeilTwitterSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.