Guardian Australia chief political correspondent Paul Karp and Peter Lewis from Essential Media discuss voter views on Australian democracy, warning signs for Anthony Albanese, support for electoral reform, and challenges with media gatekeepers.

Peter Lewis, a representative from Essential Media, joins the discussion about Peter Dutton's controversial stance on Gaza refugees. The conversation reveals mixed public opinions on Dutton's divisive tactics for political leverage. Lewis highlights shifting sentiments on immigration linked to economic fears and the growing political risks related to workers' rights. The dialogue also underscores the Labor party's struggles amidst changing political tides and the need for a narrative that fosters unity over division.

Join Paul Karp, chief political correspondent, and Peter Lewis from Essential Media as they tackle the troubling decline in public trust towards the government. They discuss voter ambivalence towards Indigenous policies stemming from the 'Close the Gap' report and the challenges Indigenous leaders face. The conversation shifts to economic pessimism affecting citizen outlook, especially with rising living costs. They highlight the crucial need for civic engagement in democracy and explore how technology can empower citizens to rebuild faith in their government.

Katharine Murphy and Peter Lewis discuss the recent poll showing no voters overtaking yes voters in the voice to parliament campaign. They also talk about voter engagement, dynamics between yes and no campaigns in a referendum, and the history of industrial relations deregulation in Australia.

New research paper on assessing p300/CBP in circulating tumor cells. Connection between SIRT2 deacetylation and p300 acetylation in prostate cancer. Use of Exclusion-based Sample Preparation to isolate CTCs. Staining optimization reveals expression of acetyl-p300 and acetyl-H3K18.