Biochemist Nick Lane discusses the origin of life on Earth and the role of oxygen. They explore the concept of a common ancestor, the hopeful monster in evolution, and the importance of water. The significance of photosynthesis and the importance of DNA and RNA are also discussed. The rise of JavaScript and predator-prey dynamics are explored. They delve into Neanderthal interbreeding, evolution and perception, and the complexity of consciousness in AI. The potential breakthroughs in biology through AI are mentioned, as well as the likelihood of bacteria on other planets. The Cambrian explosion, the origin of AI, the biology of suicide and depression, and pursuing passion in science careers are also discussed. The urgent problem facing humanity and the need for solutions are addressed.

Melvyn Bragg and guests discuss the power-packs within cells in all complex life on Earth. Inside each cell of every complex organism there are structures known as mitochondria. The 19th century scientists who first observed them thought they were bacteria which had somehow invaded the cells they were studying. We now understand that mitochondria take components from the food we eat and convert them into energy. Mitochondria are essential for complex life, but as the components that run our metabolisms they can also be responsible for a range of diseases – and they probably play a role in how we age. The DNA in mitochondria is only passed down the maternal line. This means it can be used to trace population movements deep into human history, even back to an ancestor we all share: mitochondrial Eve. With Mike Murphy Professor of Mitochondrial Redox Biology at the University of CambridgeFlorencia Camus NERC Independent Research Fellow at University College Londonand Nick Lane Professor of Evolutionary Biochemistry at University College LondonProducer Luke Mulhall

The origin of life here on Earth was an important and fascinating event, but it was also a long time ago and hasn’t left many pieces of direct evidence concerning what actually happened. One set of clues we have comes from processes in current living organisms, especially those processes that seem extremely common. The Krebs cycle, the sequence of reactions that functions as a pathway for energy distribution in aerobic organisms, is such an example. I talk with biochemist about the importance of the Krebs cycle to contemporary biology, as well as its possible significance in understanding the origin of life.Support Mindscape on Patreon.Nick Lane received his PhD from the Royal Free Hospital Medical School. He is currently a professor of Evolutionary Biochemistry at University College London. He was a founding member of the UCL Consortium for Mitochondrial Research, and is Co-Director of the UCL Centre for Life’s Origin and Evolution. He was awarded the 2009 UCL Provost’s Venture Research Prize, the 2011 BMC Research Award for Genetics, Genomics, Bioinformatics and Evolution, the 2015 Biochemical Society Award, and the 2016 Royal Society Michael Faraday Prize and Lecture. His new book is Transformer: The Deep Chemistry of Life and Death.Web siteUCL web pageGoogle Scholar publicationsAmazon author pageWikipediaSee Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Renowned guests Lisa Miller, Nick Lane, and Paul Bickley explore consciousness, life after death, and the limitations of the physical body in this thought-provoking podcast. They discuss scientific evidence for life after death, the concept of afterlife in a secular world, and the significance of love and connection in spiritual life. The speakers also debate the possibility of an afterlife in a secular society and the need for better frameworks to understand and process death.

Delving into the origin of life, the podcast explores abiogenesis theories and experiments like Miller-Urey. References to Darwin's warm pond letter and Haldane's work add depth. The RNA world hypothesis and hydrothermal vent theories are discussed, shedding light on the complexities of life's beginnings.