Murali Doraiswamy, a Professor of Psychiatry and Physician Scientist at Duke University, dives deep into the complexities of mental illness. He discusses how economic instability and cultural differences shape mental health experiences globally. The impact of social media on teenage anxiety is another hot topic. The conversation also highlights the integration of positive psychology in psychiatry, the ethical challenges of treating terminal illnesses, and the blending of Eastern and Western views on happiness, especially as we age.