Dr. Michael Grasso, an expert in autoimmune neurology, dives into the clinical nuances of NMOSD and MOGAD, highlighting their distinct features and differences from multiple sclerosis. He examines gender and ethnic disparities in these disorders, stressing the need for precise diagnostic criteria. The conversation covers effective treatment strategies, including the role of prednisone and plasma exchange. Grasso's insights into a complex case study illustrate the challenges of early diagnosis and tailored management in neuromyelitis optica.