Manish Maskey

Board-certified nephrologist involved in Vertex's IgA nephropathy research, explaining B-cell biology and the roles of BAFF and APRIL as therapeutic targets.

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Nov 9, 2025 • 18min

Targeting IgA Nephropathy (Sponsored Content)

Rachel Benton, a dedicated mother diagnosed with IgA nephropathy after a prenatal checkup, shares her emotional journey through the disease and its challenges on family life. Nephrologist Dr. Jonathan Barrett explains the biology behind IgA nephropathy and its historical underreporting. Dr. Manish Maskey discusses targeting B-cell drivers like BAFF and APRIL in research for potential therapies. Rachel’s advocacy emphasizes the importance of routine health checks, making her story both inspiring and informative.

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