Masters in Business Targeting IgA Nephropathy (Sponsored Content)
Nov 9, 2025
Rachel Benton, a dedicated mother diagnosed with IgA nephropathy after a prenatal checkup, shares her emotional journey through the disease and its challenges on family life. Nephrologist Dr. Jonathan Barrett explains the biology behind IgA nephropathy and its historical underreporting. Dr. Manish Maskey discusses targeting B-cell drivers like BAFF and APRIL in research for potential therapies. Rachel’s advocacy emphasizes the importance of routine health checks, making her story both inspiring and informative.
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Unexpected Diagnosis During Pregnancy
- Rachel discovered protein in her urine during a routine pregnancy test that led to a kidney biopsy and an IgA nephropathy diagnosis.
- The phone call confirming IgA nephropathy was brief and left her with many unanswered questions about cause and cure.
Postpartum Follow-Up Led To Biopsy
- After giving birth Rachel briefly forgot about the kidney issue but retested at nine months and proceeded to a kidney biopsy.
- She cried for two days after learning the diagnosis and struggled with uncertainty about her future health.
Rapid Kidney Function Drop Scare
- Rachel experienced a rapid drop in kidney function where it fell 30 points over two months, prompting warnings she'd need dialysis within a year.
- She later rebounded but remains uncertain whether that recovery will hold long-term.