Leo Nicolai

Join platelet experts Craig Morrell, Leo Nicolai, and Larry Frelinger as they dive into the fascinating world of platelet heterogeneity. Morrell reveals how diverse megakaryocyte origins impact platelets' varied functions and production in organs like the lung and spleen. Nicolai discusses the critical roles of procoagulant platelets in thrombosis and inflammation using innovative mouse models. Frelinger sheds light on how platelet age influences their characteristics through advanced phenotyping techniques, addressing the challenges in therapeutically targeting these essential cell subsets.