Jennifer E. Flythe, MD, MPH, a dialysis expert from the University of North Carolina, joins Kristin L. Walter, MD, MS, JAMA's Deputy Editor. They delve into the crucial decision-making process behind choosing hemodialysis or peritoneal dialysis based on patient symptoms and preferences. The discussion highlights the ineffectiveness of statins and ICDs for cardiovascular prevention in dialysis patients. They also explore managing common symptoms like pruritus and depression, while shedding light on the high mortality risk within the first six months of treatment.

James D. Douketis, MD, a specialist in anticoagulant management from McMaster University, teams up with Kristin L. Walter, MD, MS, a JAMA Deputy Editor with a focus on clinical research. Together, they dive into the nuances of managing direct oral anticoagulants (DOACs) during surgical procedures. They explore bleeding risks, the pharmacokinetics of DOACs, and tailored strategies for individual patient safety. The duo also discusses the emerging role of Dolex in perioperative care and stresses the need for healthcare professionals to stay informed.