In this fascinating discussion, distinguished immunologist Prof. Kingston Mills and neurological autoimmunity expert Dr. Anastasia Zekeridou dive deep into the powerful cytokine IL-17. They unpack its dual role in diseases like multiple sclerosis, emphasizing targeted therapies and potential risks of blocking IL-17. The guests also touch on the role of tissue-resident memory T cells and the implications of immune responses in paraneoplastic neurological syndromes. Their insights on antibody pathogenicity and the intersection of cancer treatment with neurological autoimmunity are truly enlightening.

Professor of Experimental Immunology at Trinity College Dublin, Kingston Mills, discusses the detection of the new Covid-19 variant BA.4 in Ireland, its mutations, and vaccine effectiveness. The podcast also covers the implications of a more transmissible variant displacing Omicron and the concerns surrounding monkeypox.