Karim Brohi

Karim Brohi, a leading professor in trauma resuscitation, shares his invaluable expertise on modern trauma care. He sheds light on the REFILL trial, which investigates blood component use in resuscitation. The conversation dives into the underused tranexamic acid and challenges like coagulopathy. Brohi emphasizes updating trauma activation criteria post-COVID and highlights the importance of advanced imaging for ischemic limbs. His insights provide a fresh perspective on adapting trauma management to maximize patient outcomes.

Profs Nikki Curry and Karim Brohi present the results of the CRYOSTAT-2 trial, evaluating early and empiric high-dose cryoprecipitate in patients with major traumatic hemorrhage. The panel discusses the importance of fibrinogen in hemostasis, the feasibility and findings of the Cryostat treatment trial, comparing treatment against placebo in trauma trials, military trauma care, delays in analysis and caution with small sample sizes, and the discussion on formula composition and trial framework.