A new blood test predicts psychosis risk for precise treatment, gene mutations allow different populations to thrive at extreme altitudes, and polycystic ovary syndrome is linked to cognitive decline in midlife.

Jibran Khokhar, an Associate Professor at Western University, shares insights on the neurobiology of mental illness and substance use disorders. He discusses the complex relationship between THC and psychosis, emphasizing how cannabis affects dopamine in the brain. The conversation also dives into the comorbidity of schizophrenia and substance use, the variances in THC metabolism based on sex, and the differences between vaping and smoking nicotine. Throughout, genetic influences and the challenges in addiction research are notably highlighted.