Dr. Jeffrey Rathmell, the Cornelius Vanderbilt Professor of Immunobiology, dives into T cell metabolism and its critical role in cancer. He discusses how T cells utilize fatty acids as fuel and the intriguing 'obesity paradox' in cancer immunotherapy. Rathmell also reflects on the joys of being a scientist and professor, emphasizing the importance of mentorship and collaboration in research. Explore the metabolic shifts in T cells and their implications for therapy as he shares insights into the evolving landscape of immunology.