In this thought-provoking discussion, Liron Shapira, a prominent AI risk advocate, engages with Gaëtan Selle about the existential threats posed by artificial intelligence. They dissect the crossroads of effective altruism and transhumanism while pondering the chilling notion of a potential AI apocalypse. Delving into Bayesian epistemology, Shapira examines how uncertainty shapes our understanding of AI risks. The conversation takes a fascinating turn as they explore cryonics, simulation theories, and the quest for alignment between AI and human values.