Anesthesiology experts discuss the use of methadone in outpatient surgery, addressing misconceptions about the opioid crisis. They explore the various definitions and terminologies associated with outpatient surgeries. A dose escalation study on methadone for post-surgery pain management is discussed, highlighting the importance of managing acute pain. The significance of feasibility and pilot studies in testing treatments is emphasized. Methadone's potential in perioperative practice for pain management is explored.