Dr. Jade Teta and podcast ambassador Emma Sutherland discuss the connection between metabolism, hormones, and weight management. They debunk the calorie-in vs calorie-out myth and emphasize the holistic view of metabolism as a sensory apparatus responding to stress, hormones, and temperature. Hormonal influences, including leptin, insulin, estrogen, and progesterone, on metabolism and weight management are explored. The podcast provides insights on metabolic flexibility, effective approaches to managing metabolism, signs and symptoms driving patients to seek assistance, body recomposition, leptin resistance, and cortisol's role in metabolism and hormone function.