Dr. Marco Seandel, a researcher from Weill Cornell Medical College, discusses his groundbreaking work on spermatogonial stem cells and how they reveal mutations in aged male sperm. He dives into the implications of paternal age on genetic disorders, such as Apert syndrome. The conversation is rich with insights on stem cell behavior and the balance of mutations in sperm development. Alongside humor, they touch on the challenges of collecting tissue samples and the inequities faced by researchers in academia, making for an engaging exploration of science.