Ep. 24: Sperm Stem Cells Featuring Dr. Marco Seandel

Aug 4, 2014

Dr. Marco Seandel, a researcher from Weill Cornell Medical College, discusses his groundbreaking work on spermatogonial stem cells and how they reveal mutations in aged male sperm. He dives into the implications of paternal age on genetic disorders, such as Apert syndrome. The conversation is rich with insights on stem cell behavior and the balance of mutations in sperm development. Alongside humor, they touch on the challenges of collecting tissue samples and the inequities faced by researchers in academia, making for an engaging exploration of science.

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Intro

00:00 • 2min

Exploring Scientific Discoveries and Listener Engagement

01:41 • 4min

Exploring Animal Behavior and Groundbreaking Scientific Discoveries

05:57 • 5min

Controversies and Advances in Stem Cell Research

10:43 • 17min

The Paternal Age Effect: Implications for Genetic Disorders

27:47 • 6min

Stem Cells and Paternal Genetics

33:27 • 20min

Sperm Racing and Research Realities

53:26 • 13min

Guest: Dr. Marco Seandel from Weill Cornell Medical College joins the hosts to talk about his latest paper published in Stem Cell Reports, where he used sperm stem cells to uncover novel info about mutations in aged male sperm. Resources and Links Learning The Smell Of Fear: Mothers Teach Babies Their Own Fears Via Odor, Animal Study Shows The Habenula Encodes Negative Motivational Value Associated with Primary Punishment in Humans A Highly Abundant Bacteriophage Discovered in the Unknown Sequences of Human Faecal Metagenomes Mysterious X-rays Might Hint at Dark Matter Researchers Find First Sign that Tyrannosaurs Hunted in Packs The Black Death in China Longitudinal Changes in Total Brain Volume in Schizophrenia: Relation to Symptom Severity, Cognition and Antipsychotic Medication Junk Food Could Destroy Your Sense of SMELL, Scientists Warn Mechanisms of CFTR Functional Variants That Impair Regulated Bicarbonate Permeation and Increase Risk for Pancreatitis but Not for Cystic Fibrosis Genetic Cause of Common Breast Tumors Found Lawsuit Claims Stem Cells Unsafe California's Stem Cell Scandal Gets Worse Sugar Mimic Helps Embryonic Stem Cells Develop Toward Nerve Cells Teeth Sprout from Glia-Derived Stem Cells Stem Cell Research Could Lead to New Muscle Repair Treatments Stem Cell Therapy Could Lead to HIV Cure Functional and Molecular Defects of Hipsc-Derived Neurons from Patients with ATM Deficiency Spider Silk for Xeno-Free Long-Term Self-Renewal and Differentiation of Human Pluripotent Stem Cells Role of Astroglia in Down's Syndrome Revealed by Patient-Derived Human-Induced Pluripotent Stem Cells Generation Of Induced Pluripotent Stem Cells From Virus Freein Vivo Reprogramming of BALB/C Mouse Liver Cells Gene Expression Variability as a Unifying Element of the Pluripotency Network Enhanced Fitness of Adult Spermatogonial Stem Cells Bearing a Paternal Age-Associated FGFR2 Mutation Photo Reference: Courtesy of Dr. Marco Seandel Subscribe to our newsletter! Never miss updates about new episodes. Subscribe