Dr. Juergen Knoblich, a scientist at the Institute of Molecular Biotechnology in Vienna and senior author on a groundbreaking Nature paper, discusses innovative approaches in stem cell research. He elaborates on in vivo reprogramming techniques that transform somatic cells into induced pluripotent stem cells. Additionally, Knoblich shares insights into the creation of mini cerebral cortices from human embryonic stem cells, exploring their implications for understanding brain development and potential therapies.