Jane Metcalf, co-founder of Wired Magazine and board chair of the Human Immunome Project, teams up with Dr. John Tsang, a Yale systems immunologist, to discuss the ambitious Human Immunome Project. They explore how mapping the immune system can revolutionize personalized healthcare by integrating diverse data and methodologies. Listeners learn about the complexities of immune responses, advances in immunotherapy, and the critical need for longitudinal research to understand health disparities and improve disease treatments.