Dr. Bharat Kumar, a clinical rheumatologist and allergy immunologist at the University of Iowa, sheds light on inborn errors of immunity (IEI). He discusses the challenges in diagnosing IEI, especially their symptom overlap with rheumatic diseases. The importance of a detailed clinical history and collaboration between specialties is emphasized. Dr. Kumar also covers advancements in treatments, the role of cytokine profiles, and the significance of specialized training in allergy immunology for better patient care.