In this lively discussion, Irish comedian Des Bishop, known for his stand-up special "Of All People," shares hilarious insights on male sexuality, including straight guys' surprising interests in butt play. He joins Dan Savage to explore the dynamics of relationships, from a woman's shocking discovery about her boyfriend's hidden family to a married woman's journey into burlesque and exploring her bisexuality. The pair also tackle the sensitive issue of a partner's declining hygiene, offering hilarious yet honest advice on maintaining intimacy.

Des Bishop, a renowned comedian celebrated for his stand-up specials, shares his unique journey in this engaging conversation. He humorously recounts having a testicle removed and the transition from Irish to New York comedy scenes. Des also shares his ambitious attempt to learn Mandarin for performances in China, reflecting on the cultural challenges involved. The discussion touches on everything from the quirks of airport regulations to humorous childhood escapades, offering an entertaining blend of anecdotes and insights.