Dena Dubal, a physician-scientist, discusses the longevity factor klotho and its impact on brain health, cognitive function, and potential in treating Alzheimer's disease. Topics include klotho production, regulation, decline with age, benefits on brain health, cognitive enhancement, and therapeutic implications for neurodegenerative diseases.

Everybody gets older, but not everyone ages in the same way. In this episode, Steven Strogatz speaks with Judith Campisi and Dena Dubal, two biomedical researchers who study the causes and outcomes of aging, to understand how age works - and what scientists know about postponing or even reversing the aging process.