Chris Sacca is the Founder and Chairman @ Lowercase Capital, one of the best performing funds in the history of venture capital with a portfolio including Uber, Stripe, Twitter, Instagram, Twilio, Docker and many more. Why does Chris believe we have bred a generation of asshole kids? What is the right way to negotiate with children? How has that impacted how he manages his team? Anne Wojcicki is the Founder & CEO @ 23andMe, offering DNA testing with the most comprehensive ancestry breakdown, personalized health insights, and more. How did having kids change Anne's approach to time allocation and risk? Harley Finkelstein is the President of Shopify. Over the last 12 years, Harley has partnered with Tobi to the tune of building Shopify’s revenue to over $4.6BN in 2021 and the team to over 10,000 employees.  Does Harley believe he has always been a good father? What changes has Harley made to be more present and there for his children? Why does Harley advise couples therapy as early in a relationship as possible? Deena Shakir is a Partner at Lux Capital, one of the leading firms investing in emerging science and technology ventures at the outermost edges of what is possible. What specific negotiation tactics from parenting can be applied to business? How can a parent show their children they listen, they understand and are there for them? Why does Deena believe children make you more productive and more efficient? Eric Liaw is a General Partner @ IVP, one of the leading later-stage venture capital and growth equity firms of the last decade with $8.7 billion of committed capital and a 40-year IRR of 43.1%. What have been the biggest challenges for Eric of managing family and work? What have been some of Eric's biggest lessons in terms of how he communicates about his work to his family? Scott Dietzen is Vice Chairman of the Board of Pure Storage and served as the Company’s CEO from 2010 to 2017. Under his leadership, Pure grew to thousands of employees and completed an IPO in 2015. What can parents learn from nature programs? What core elements of parenting are directly transferrable to management?

Serial entrepreneur and cancer survivor, Lisa Alderson, pitches her startup, Clarified Precision Medicine, to Deena Shakir of Lux Capital. They discuss the go-to-market strategy, using genomics in oncology, building a moat, making money, SAFEs vs priced rounds, and keeping a motivated founding team.

Uber CEO Dara Khosrowshahi discusses the company's positive earnings and future growth. Deena Shakir talks about venture capital investing. The CEO of Stocktwits looks at Elon Musk's ambitions. The podcast also explores the future of healthcare, telemedicine, and innovation refunds.

After news broke that meditation app Headspace and on-demand mental health care platform Ginger were merging, we couldn't resist hopping on the mics to do a bonus episode. And, because we were in the mood for hot takes, Natasha and Alex held the conversation on Twitter Spaces. The special guests we had on, who we'll get to down below, did not disappoint.It's a quick show, but the tl;dr is that you want to listen if you're curious why a meditation app would get into therapy, the precedent by Lyra Health and Calm, and how consolidation looks for the sector going forward.Here's who helped us understand and contextualize the news: Lux Capital partner Deena Shakir (who is also coming to Disrupt, incidentally) Chrissy Farr of OMERS Ventures (who you may also know as a former CNBC reporter in the healthech space) 7WireVentures' Alyssa Jaffee (who needs her own podcast because she was shining during the Spaces) And, special shout out to Ginger CEO Russell Glass, who joined the Space but wasn't able to come up on stage due to technical difficulties. Twitter Spaces are fun, but the platform is still a bit nascent so goofs can bedevil live production.However, we managed to get some notes from him via email, so let's take a quick look at those: Glass said that he agreed with "what Chrissy Farr and others said about there simply not being enough therapists in the market today to meet the overwhelming demand," adding that there's "real global need today for what Headspace Health can offer - a scaled, comprehensive platform that can truly democratize mental healthcare." He also doubleclicked on the discussing regarding future "meaningful market consolidation," noting that he expects to see it "especially" happen in "areas that address higher acuity care for severe mental illness.” Make sure you are following the podcast on Twitter so that you catch us when we go live. These are meant to be spontaneous pop up shows, so your best bet is to turn on notifications to never miss our Spaces. Ok that's all. Thanks everyone! Credits: Equity is produced by Theresa Loconsolo with editing by Kell. Bryce Durbin is our Illustrator. We'd also like to thank the audience development team and Henry Pickavet, who manages TechCrunch audio products.

Deena Shakir, General Partner at Lux Capital, discusses her background as the daughter of Iraqi immigrants, Lux's behavior traits, portfolio management as a team sport, establishing company culture, and the significance of data on diversity in venture.