In this engaging discussion, Matt Kielty, a Radiolab reporter, delves into the compelling origins of the 'born this way' idea alongside Dean Hamer, a geneticist known for his research on a potential genetic link to male homosexuality, and Joanna Wuest, a political scholar exploring the historical context of this concept. They tackle the complexities of sexual orientation, the interplay of genetics and identity, and the societal implications of advocating for inherent traits. The conversation also reflects on evolving narratives within LGBTQ+ rights and the fluidity of attraction.