Praveen Sethupathy, a physiological genomics professor at Cornell, and David Rudge, a biological sciences professor at Western Michigan, dive into the nature of knowledge. They question whether science is the sole path to understanding, exploring alternative ways of knowing such as culture and personal experiences. The discussion touches on the interplay of faith and science, and the importance of critical thinking in navigating scientific authority. They also share personal journeys that blend scientific inquiry with spiritual exploration.