Leading experts Stephan Achenbach, Carlos Aguiar, Emma Svennberg, David Capodanno, and Nicolle Kraenkel discuss the latest developments in cardiovascular medicine, including new pharmacologic approaches for hypertrophic obstructive cardiomyopathy and advancements in intravascular imaging in coronary interventions. They also highlight the Atesia trial, which compares oral anticoagulant therapy for subclinical atrial fibrillation and discuss the top cardiology papers of 2023, including a study on the blood pressure-lowering effects of tomatoes.