In this engaging discussion, Charlotte Blease, a health informaticist, and Cosima Locher, a psychologist, delve into the fascinating concept of the nocebo effect, where negative beliefs can lead to real health consequences. They reveal how our expectations, shaped by narratives and technology, influence health outcomes, especially seen during the COVID-19 vaccine rollout. With insights on the power of communication, the role of empathy, and effective mindset training, they empower listeners to take control of their health through awareness.