Jan Jansen and Marion Campbell present the results of the UK-REBOA trial, investigating the use of REBOA in trauma patients. They discuss the enrollment process, data collection, and clinical trial results. The podcast also covers the importance of reducing time to hemostasis in hemorrhagic deaths and the challenges of managing blunt trauma injuries. Additionally, they explore the difficulties of intubation in children and evaluating efficacy.

Profs Nikki Curry and Karim Brohi present the results of the CRYOSTAT-2 trial, evaluating early and empiric high-dose cryoprecipitate in patients with major traumatic hemorrhage. The panel discusses the importance of fibrinogen in hemostasis, the feasibility and findings of the Cryostat treatment trial, comparing treatment against placebo in trauma trials, military trauma care, delays in analysis and caution with small sample sizes, and the discussion on formula composition and trial framework.