Dr. Anu Lala, an expert in heart failure research, and Dr. Martha Gulati, a renowned prevention specialist and author, explore the complexities of heart failure with preserved ejection fraction (HFpEF) in women. They discuss unique clinical presentations and the significance of gender-specific risk factors, including obesity and sleep apnea. The conversation highlights innovative treatment strategies, such as SGLT2 inhibitors, and emphasizes the need for a holistic, multidisciplinary approach to improve outcomes for women facing HFpEF.