In this insightful discussion, Dr. George Willis, an expert in endocrine emergencies from the University of Texas, and Dr. Alyssa Lewis, a critical care specialist from Toronto, dive into the intricacies of decompensated hypothyroidism. They clarify why 'myxedema coma' is a misleading term and discuss crucial ways to differentiate it from sepsis and overdose. Topics include the importance of cortisol testing, risks associated with intubation, and strategies for effective management, emphasizing the critical need for early diagnosis and proper treatment in these complex cases.