Alex Rampotas, MD
Clinician‑researcher at University College London focused on developing CAR‑T cell therapies for myelofibrosis, leading preclinical development and translational studies for CALR‑directed cellular approaches.
Best podcasts with Alex Rampotas, MD
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Jul 14, 2025 • 21min
Targeting mutant CALR in MPNs with antibodies & cellular therapy: the potential for disease modification
This conversation features Claire Harrison, a haematologist with expertise in MPNs, Alex Rampotas, a clinician-researcher focused on CAR-T therapies, Jean-Jacques Kiladjian, a hematologist with a deep understanding of MPN biology, and John Mascarenhas, involved in MPN clinical trials. They explore the potential of targeting mutant CALR in MPNs. Key insights include the promising early results of the INCA33989 trial, the development of CAR-T therapies aimed at mutant CALR, and innovative approaches using organoid models to test immunotherapies effectively.
Feb 22, 2024 • 13min
Updates with the use of CAR-T therapy in ALL: ongoing challenges, strategies to overcome resistance & future outlooks
Renowned experts discuss challenges & advancements in CAR-T therapy for Acute Lymphoblastic Leukemia. Topics include dual targeting of CD19 & CD22, management considerations for patients, outcomes in post-transplant relapse, and strategies for T cell ALL treatment.
