Dr. Aaron Bodansky, an Assistant Professor of Pediatric Critical Care at UCSF, and Dr. Adrienne Randolph from Boston Children’s Hospital discuss cutting-edge research on Multisystem Inflammatory Syndrome in Children (MIS-C). They unpack the immune responses linked to MIS-C, highlighting how molecular mimicry may trigger autoimmune diseases. The conversation also delves into the role of SARS-CoV-2 in this condition and examines the immune dysregulation seen in affected children, with implications for understanding long COVID and other related disorders.