Anabolic Bodybuilding Best Primobolan Cycle? Advice Before Starting Gear, Thoughts On T3 & Clen, Metformin Lowers IGF-1?
Jan 9, 2026
Dive into the intriguing debate over berberine versus metformin and their impacts on health. Discover the truth about 19-nors and prolactin before exploring when Primobolan truly shines in your cycle. Big Paul provides insights on managing estrogen levels and tackling rebound strategies after a break. Learn about sodium-potassium balance and its effect on water retention, then weigh the pros and cons of T3 and Clen for fat loss. Finally, find out the best back exercises for sensitive lifters.
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Use Berberine First, Metformin As Backup
- Start with berberine for carb days and reserve metformin as a later option when fasting glucose is persistently high.
- Consider GLP-1 triple agonists before metformin and avoid stacking metformin and berberine unnecessarily.
Estrogen Drives Prolactin Problems With 19-Nors
- 19-nor steroids (like Deca) suppress dopaminergic tone and can indirectly raise prolactin symptoms via progesterone effects.
- High estrogen amplifies progesterone sensitivity, so poor estrogen control often drives prolactin-like side effects, not the 19-nor alone.
Primobolan Works At Moderate Doses
- You don't need 600 mg/wk to get benefit from Primobolan; lower doses still modulate estrogen and SHBG positively.
- Use Primo as an anabolic to improve testosterone's effectiveness rather than defaulting to an aromatase inhibitor.