Methylene Blue & Mitochondria: How This Compound Fights Alzheimer's and Brain Aging

I'm excited to share my conversation with Dr. Scott Sherr, where we dive deep into methylene blue - a compound you've probably seen all over social media lately (those blue tongues!). As someone whose primary research focuses on Alzheimer's disease, I was fascinated to explore the science behind this molecule that dates back to the 1870s and was actually the first drug registered with the FDA in 1897.  

The most fascinating insight for me was learning how methylene blue can serve as an electron acceptor in our mitochondria - essentially functioning as a substitute for oxygen when our cells are under stress. This explains why it shows promise for everything from traumatic brain injury to cognitive enhancement and even as a potential alternative to stimulant medications. 
 
If you're interested in optimizing brain performance, understanding mitochondrial health, or simply curious about this blue compound that's suddenly everywhere, this episode provides both the scientific foundation and practical applications you need.
 
Subscribe to The Neuroscience Experience for more conversations at the intersection of brain science and performance. I'm committed to bringing you evidence-based insights that you can apply to your own health journey. 

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Timestamps 
00:00 Introduction 
02:30 Methylene Blue's Role in Neurotransmitter Regulation 
07:54 Mitochondrial Health and Methylene Blue 
17:02 Methylene Blue and Modern Health Challenges 
25:27 Methylene Blue in Hypobaric and Hyperbaric Environments 
29:47 Understanding Hyperbaric Oxygen Therapy 
32:27 Methylene Blue: A Mitochondrial Rescue 
36:52 Bioavailability of Methylene Blue 
42:17 Dosing and Applications of Methylene Blue 
47:46 Combining Methylene Blue with Other Treatments 
54:02 Conclusion and Further Resources

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The Neuro Experience Podcast is proud to have hosted: Dr Andrew Huberman, Dr Gabrielle Lyon, Dr Layne Norton, Thomas DeLauer, Shawn Stevenson, Dr. Rocio Salas-Whalen, Saad Alam, Uma Naidoo, Dr. Lanna Cheuck, Angela Lee Pucci, Jillian Turecki, Dr. Jordan Feigenbaum, Dr. Darren Candow, Dr. Sue Varma, Evy Poumpouras, Dr Casey Means, Renee Deehan, Dr Chris Palmer, Dr Charles Brenner, Dr Joe Zundell, Dr Ray Dorsy, Dr Dale Bredeson, Dr. Ben Bikman