John discusses how the latest injury to Brock Purdy could lead to the downfall of the 49ers if Sam Darnold doesn't pan out. Then, he dives into the Browns and their QB issues with Watson having to miss another game. Later, John talks about two possible running backs that could be on the move before the trade deadline.

Finally, John answers your questions in today's mailbag.

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3 and Out - Purdy Out, Watson Hurt, Possible Trades