TED Talks Daily How ibogaine could treat depression and anxiety | Nolan Williams
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Dec 5, 2025 
Nolan Williams, an interventional neuropsychiatrist and director at the Stanford Brain Stimulation Lab, dives into the potential of ibogaine for treating PTSD, anxiety, and depression. He discusses its traditional use and the need for careful medical supervision. Personal stories highlight its transformative impact on veterans and others in recovery. Williams also examines the historical skepticism around plant-based treatments and advocates for open-minded research on psychedelics, while addressing safety concerns and regulatory hurdles.
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Anti-Fruiter Parallel To Psychedelic Resistance
- Historical resistance to simple plant remedies delayed lifesaving treatments like citrus for scurvy by generations.
- Nolan Williams uses this analogy to warn that ideological rejection could slow adoption of psychedelics.
Veteran's Life Changed By Ibogaine
- Marcus Capone, a Navy SEAL, sought ibogaine in Mexico after standard treatments failed and believed it saved his life.
- Nolan Williams describes multiple veterans who reported dramatic recovery after supervised ibogaine treatment.
Eric's Recovery Weekend
- Eric described a profound shift after ibogaine where he stopped drinking and smoking and re-engaged with family.
- He said the experience allowed him to confront traumas and begin the real therapeutic work afterward.